Take I-71 North. Continue on I-71, passing the I-64 split, and exit at Zorn Avenue. Turn left onto Zorn, taking care as you cross the median. Make a right turn onto River road at the light (Chevron Station on the corner). Turn right onto Blankenbaker Lane, approximately 6 miles from downtown Louisville, at the traffic light. You will proceed gradually uphill as you travel away from the river, and will find the entrance to the Locust Grove parking lot on your left, immediately past Twin Hill (on the right).
From Downtown Louisville
Take either the I-71 to Zorn Avenue route described above, or if you are already close to the riverfront, just take River Road all the way out to Blankenbaker Lane.
From points along the Watterson Expressway (I-264)
Take the Watterson eastward to the Brownsboro Road (U. S. 42) exit. At the end of the ramp, turn left and proceed to the third traffic light. Turn right onto Blankenbaker Lane. Locust Grove will come into view within about 1-1/2 miles, just as you crest a small ridge. Make a right turn into the parking lot, just after passing the historic house.